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Facilities and Infrastructure

The Mycobacteria Research Laboratory is supported by a robust portfolio of state-of-the-art instrumentation and specialist experimental infrastructure that enables research at the interface of molecular microbiology, biochemistry, microbial genetics, infection biology, antimicrobial resistance and translational discovery science.

Our facilities support a wide range of experimental activities, including molecular and cellular microbiology, mycobacterial culture, protein expression and purification, microbial phenotyping, imaging, automated assay workflows, and antimicrobial susceptibility testing.

Key laboratory platforms include the Nuclera eProtein Discovery System, ÄKTA Purifier, Beckman Coulter Optima XPN-80 Ultracentrifuge, Thermo Scientific Multidrop Combi (i-SPOT-AMR robotic platform), SpectraMax iD3 Plate Reader, Bio-Rad Gene Pulser Xcell Electroporator, NanoDrop 2000 Spectrophotometer, Invitrogen iBright 750 Imaging System, Zeiss microscopy systems, incubator shakers, CO₂ incubation facilities, laminar airflow cabinets, autoclaves, and ultra-low temperature sample storage systems.

Together, these facilities provide a strong platform for cutting-edge basic and translational research, while also supporting collaborative partnerships, research training and innovation-led approaches to tackling infectious diseases and antimicrobial resistance.

Selected Equipment

Molecular Biology and Genetic Analysis

  • MJ Research Peltier Thermal Cycler
  • Prime PCR Machines
  • Bio-Rad Gene Pulser Xcell Electroporator
  • Labnet Power Station 300 Plus
  • Thermo Scientific NanoDrop 2000 Spectrophotometer
  • Invitrogen iBright 750 Gel Imaging System
  • UVP Transilluminator (Analytik Jena)
  • Ribolyser Savant BIO101 FastPrep FP12

Protein Science and Biochemical Analysis

  • Nuclera eProtein Discovery System
  • ÄKTA Purifier (GE Healthcare)
  • Beckman Coulter Optima XPN-80 Ultracentrifuge
  • SpectraMax iD3 Plate Reader (Molecular Devices)

Automation and High-Throughput Screening

  • Thermo Scientific Multidrop Combi (i-SPOT-AMR robotic system)
  • Plate Incubator Refrigerator

Microscopy and Imaging

  • Zeiss Stemi V4 Stereo Microscope
  • Zeiss Primo Vert Microscope
  • Zeiss Primo Star Microscope

Microbial Culture, Growth and Incubation

  • New Brunswick Scientific Incubator Shakers
  • Thermo Scientific Incubator Shaker (MAXQ 4000)
  • New Brunswick Galaxy 170S CO₂ Incubator
  • Genlab Incubator (37°C)
  • Binder Incubator (for agar plates)
  • Clifton Water Bath (NE1D4)

Sterilisation, Safety and Containment

  • Classic Prestige Medical Autoclave
  • Rodwell Autoclaves (ENSIGN and MONARCH)
  • NuAire Laminar Airflow Cabinet
  • EVS Laminar Airflow Cabinet

Cold Storage and Sample Preservation

  • New Brunswick U725G Ultra-Low Temperature Freezer (–80°C)
  • Eppendorf CryoCube F440h Freezer (–80°C)
  • Liebherr MedLine Freezers (–20°C)
  • Labcold Spark-Free Laboratory Freezer (–20°C)
  • Labcold Spark-Free Refrigerator (4°C)
  • Liebherr Freezer and Refrigerator Units (–20°C and 4°C)

Core Laboratory Equipment

  • Techne Heat Block (FDB02AD)
  • Rocker (SK-D1807-E)
  • Eppendorf Centrifuge (5424)
  • Benchmark myFuge™ Mini Centrifuge (C1008R)
  • Sartorius ROTINA 420-R Centrifuge
  • Spectrafuge Centrifuge (JENCONS-PLS)
  • Vortex-Genie 2 Mixer (G560E)
  • SB3 Rotator
  • Stuart Scientific Colony Counter
  • Stuart Hotplate Stirrer
  • Mettler Toledo pH Meter
  • Milli-Q Millipore Water Purification System
  • Scotsman Ice Machine
  • Analytical and Precision Balances
  • Microwave