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Dr Clare Sansom

Senior Associate Lecturer

Contact details

tel: +44 (0)20 7631 6839
email: c.sansom@mail.cryst.bbk.ac.uk

Room 359, Department of Biological Sciences, main building, Malet Street, London

Research highlights

International Union of Crystallography (IUCr) 2017

Dr Sansom attended this conference in Hyderabad and wrote a comprehensive blog on speakers and events.

Science Week 2016

Dr Sansom was a speaker on our Science Week 2016 discussion panel: Inspired by Science: women scientists tell their stories [video: 47 mins]

Teaching

  • My main teaching responsibilities are for the part-time MSc course in Structural Molecular Biology by distance learning. I have been involved with this innovative course since its first module, Principles of Protein Structure (PPS), was introduced in 1996. I write much of the online teaching material for the PPS course, ensuring that the content is kept up to date scientifically in this very fast-moving field.
    I run interactive tutorials in real time using an Instant Messenger system; maintain a blog relating research developments to the content of this course; and assess and examine students. I also assess and examine students on the Techniques in Structural Molecular Biology module, which is one of the second-year options for this MSc. I give a few lectures a year and occasionally supervise project students on the face-to-face MSc in Bioinformatics with Systems Biology.

Research

  • I maintain a small research interest in protein bioinformatics, initially in collaboration with Professor David Moss and now as a member of Dr Adrian Shepherd’s research group, and through supervising MSc students. My current research interests involve predicting the function and mechanism of immune system proteins and modelling the structures of G-protein coupled receptors.

Selected publications (since 2009)

    • Shepherd AJ, Skelton S, Sansom CE, Gomez K, Moss DS & Hart DP (2014). A large-scale computational study of inhibitor risk in non-severe haemophilia A. Brit J Haematol, in press.
    • Shublaq N, Sansom C & Coveney PV (2013). Patient-specific modelling in drug design, development and selection including its role in clinical decision-making. Chem Biol Drug Des 81(1): 5-12.
    • Halling-Brown M, Pappalardo F, Rapin N, Zhang P, Alemani D, Emerson A, Castiglione F, Duroux P, Pennisi M, Miotto O, Churchill D, Rossi E, Moss DS, Sansom CE, Bernaschi M, Lefranc MP, Brunak S, Lund O, Motta S, Lollini PL, Murgo A, Palladini A, Basford KE, Brusic V & Shepherd AJ (2010). ImmunoGrid: towards agent-based simulations of the human immune system at a natural scale. Philos Trans A Math Phys Eng Sci. 368(1920): 2799-815.
    • Halling-Brown M, Shaban R, Frampton D, Sansom CE, Davies M, Flower D, Duffield M, Titball RW, Brusic V & Moss DS (2009). Proteins accessible to immune surveillance show significant T-cell epitope depletion: Implications for vaccine design. Mol Immunol. 46(13): 2699-705.
    • Halling-Brown MD, Moss DS, Sansom CE, Shepherd AJ (2009). A computational Grid framework for immunological applications. Philos Trans A Math Phys Eng Sci. 367(1898): 2705-16.

External roles and professional interests

  • I also work freelance as a lecturer, bioinformatics consultant and science writer. Examples of my outside work that are relevant to my position at Birkbeck include the following:
    • I am a visiting professor at Adam Mickiewicz University in Poznan, Poland where I teach an annual course in structural bioinformatics and drug design. Between 2001 and 2011 my teaching there was funded through an Erasmus grant to Birkbeck for staff mobility; since 2012 I have taught on an MSc in Biotechnology funded through the European Social Fund.
    • I am a Fellow of the Centre for Distance Education, which supports research, collaboration and knowledge sharing in the fields of distance education and e-learning, particularly within the colleges of the University of London.
    • I was Assistant Editor of the textbook Computational Biomedicine which was published by Oxford University Press in June 2014 (with senior editor Prof. Peter Coveney of UCL).
    • I have reported on a number of important events hosted by the ISMB, including its biannual symposia and retreats, and I contribute to Birkbeck’s events blog.

    I am a fellow of the Higher Education Academy, a member of the International Society for Computational Biology and of the Biochemical Society, and an associate member of the Association of British Science Writers.
    More information about my freelance work and interests is available on my Linked In profile.