Professor Carolyn Moores
Professor of Structural Biology
Contact details
email: c.moores@mail.cryst.bbk.ac.uk
tel: 020 7631 6858
fax: 020 7631 6803
About Professor Carolyn Moores
Research interests
The microtubule cytoskeleton is essential for many cellular processes including cell division, motility, definition of cell architecture and differentiation. Our research is focused on understanding microtubule organisation and dynamics, and how these are harnessed for the life and health of the cell. Microtubule regulation and organization by a plethora of proteins is adapted to different functional contexts. We use a combination of biochemistry, biophysics and structural biology by cryo-electron microscopy to elucidate the mechanisms by which kinesin motors and microtubule associated proteins interact with and regulate microtubules.
Professor Moores gave her inaugural lecture on June 1 2015: Microtubules and Microscopes: exploring the cytoskeleton [Birkbeck event blog]
Recent publications
The divergent mitotic kinesin MKLP2 exhibits atypical structure and mechanochemistry.
Atherton J, Yu IM, Cook A, Muretta JM, Joseph A, Major J, Sourigues Y, Clause J, Topf M, Rosenfeld SS, Houdusse A, Moores CA.
Elife. 2017 Aug 11;6. pii: e27793. doi: 10.7554/eLife.27793.
