Dept of Biological Sciences | Our staff | Academic staff | Professor Carolyn Moores
Document Actions

Professor Carolyn Moores

Professor of Structural Biology

Contact details

tel: 020 7631 6858
fax: 020 7631 6803


About Professor Carolyn Moores


Research interests

The cytoskeleton is essential for many cellular processes including cell division, motility, definition of cell architecture and differentiation. Our current research is focused on understanding microtubule organisation and dynamics, and how these are harnessed for the life and health of cells. Microtubule regulation and organization by a plethora of proteins is adapted to different functional contexts. We use a combination of biochemistry, biophysics and structural biology by cryo-electron microscopy to elucidate the mechanisms by which kinesin motors and microtubule associated proteins interact with and regulate microtubules.

Major funding from ERC Synergy Grant for ArpComplexity research: Birkbeck to jointly lead major research project into muscle development, function and disease [October 2018]

News story on Professor Moores' research: Birkbeck research project will provide new insight into the 'building blocks' of our brains [November 2017]

Professor Moores gave her inaugural lecture on June 1 2015: Microtubules and Microscopes: exploring the cytoskeleton [Birkbeck event blog]

Recent papers

4.5 Å cryo-EM structure of yeast kinesin-5-microtubule complex reveals a distinct binding footprint and mechanism of drug resistance.

von Loeffelholz O, Pena A, Drummond DR, Cross R, Moores CA (2019) J Mol Biol, In press

Microtubule structure by cryo-EM: snapshots of dynamic instability.

Manka SW, Moores CA (2018) Essays in Biochemistry, In press

The role of tubulin–tubulin lattice contacts in the mechanism of microtubule dynamic instability

Manka SW, Moores CA (2018) Nat Struct Mol Biol 25, 607